4]diazepine-6-acetic acid
JQ-1 (carboxylic acid) ；6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-triMethyl-, (6S)-
CAS: 202592-23-2
Molecular Formula: C19H17ClN4O2S
4]diazepine-6-acetic acid - Names and Identifiers
4]diazepine-6-acetic acid - Physico-chemical Properties
| Molecular Formula | C19H17ClN4O2S |
| Molar Mass | 400.88 |
| Density | 1.51±0.1 g/cm3(Predicted) |
| Boling Point | 661.6±65.0 °C(Predicted) |
| Solubility | DMSO : 100 mg/mL (249.45 mM; Need ultrasonic) |
| pKa | 4.11±0.10(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| In vitro study | (+)-JQ-1 is a potent, specific, and reversible BET bromodomain inhibitor, with IC 50 s of 77 and 33 nM for the first and second bromodomain (BRD4(1/2)). (+)-JQ-1 also activates autophagy. |
4]diazepine-6-acetic acid - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.495 ml | 12.473 ml | 24.945 ml |
| 5 mM | 0.499 ml | 2.495 ml | 4.989 ml |
| 10 mM | 0.249 ml | 1.247 ml | 2.495 ml |
| 5 mM | 0.05 ml | 0.249 ml | 0.499 ml |
Last Update：2024-01-02 23:10:35
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Product Name: JQ-1 (carboxylic acid) ；6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-triMethyl-, (6S)- Visit Supplier Webpage Request for quotation
CAS: 202592-23-2
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CAS: 202592-23-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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